Beknazarova, Manzura2025-11-222025-11-222025-03-012690-9626https://dspace.kstu.uz/xmlui/handle/123456789/2949The article examines regional cooperation and technological integration strategies used to increase cluster synergy. Methods of increasing the synergistic effect of inter-industry cooperation, pooling of resources and innovative cluster models are analyzed. Using econometric models, advanced methods and approaches are recommended for analyzing relations between regions, resource flows and investments, as well as modeling the impact of interregional clustering on economic stability. The article reveals opportunities for deeper understanding and practical application of interregional clustering for sustainable economic development.synergetic effect in the process of clustering, synergetics, competitiveness in the global economy, cluster synergySynergetic Approaches of Business Entity Clusters in Regional DevelopmentArticle